Mossakowski Medical Research Centre Polish Academy of Sciences

Established in 1967, the Institute consists of 18 departments including 7 clinical research units directly collaborating with university hospitals and 4 independent laboratories. Topics of research interest contain:

  • basic and clinical neurophysiology,
  • neurochemistry,
  • neuropathology,
  • clinical pathophysiology,
  • neurosurgery,
  • applied physiology,
  • renal physiology,
  • transplantation,
  • immunology,
  • experimental pharmacology and bioinformatics

The regulatory mechanisms underlying the functional, metabolic, and structural homeostasis of the organism in healthy state and under selected pathological conditions are studied, including brain ischemia, degenerative disorders of the central nervous system (Alzheimer’s disease in particular), hepatic encephalopathy, hypertension, diabetes, neuromuscular diseases, trauma of the central nervous system. Of important scientific but also potentially practical impact are various studies confined to new diagnostic methods for brain tumors, the synthesis of new biologically active compounds (e.g. analgesic peptides or nucleosides directed selectively against tumor cells), and umbilical cord stem cells which can be converted into brain cells. An integral part of the Institute is the (NIH-certified) Animal House, where over 20 small rodent models including several unique transgenic animals are bred under specific pathogen free conditions.

The Scientific Council of the Institute is authorized to confer the academic degrees of PhD and DSc (habilitation) in medical sciences, in the fields of medicine and medical biology.

There are ongoing efforts to integrate scientific activities of institutions conducting biomedical research in the Ochota Campus area. One is the Biocentrum Ochota Consortium initiative which encompasses the six institutes of the Polish Academy of Sciences and its aim is to share resources, to identify deficiencies and to work jointly on enriching infrastructural, technical and intellectual environment of the institutes involved.

In 2012, in the collaboration with Medical University in Bialystok, MMRC got the status of a Leading National Research Centre (KNOW) for years 2012-2017. Also in 2012 MMRC established the collaborations in research and education with MD Anderson Cancer Center (MDACC) in Huston USA by joining the Sister Institution Network.

MMRC is a the member of the Centre for Preclinical Research and Technology Consortium (CePT) which main goal is to conduct research on the most common civilizational diseases, especially: neoplastic, neurological and vascular, as well as ageing and age – related diseases.

MMRC coordinates co-operative connections “Mazovian Peptide Cluster” and “Alice Med – Advanced Laboratories in Centre of Excellence”, both founded in 2011 and "Pain Relief Scientific Cluster" founded in 2012.

In the years 2012-2014, MMRC will also coordinate an international project financed within the ERA_NET NEURON 2011 Programme “European Research Projects on Cerebrovascular Diseases” entitled: "MRI Navigated Enhancement of Mesenchymal Stem Cell (MSC) Homing Toward Stroke Lesion – Evaluating an Impact on Animal Recovery with Behavioral Testing and Imaging".

The MMRC is the exclusive owner of an internationally recognized scientific journal Folia Neuropathologica (2012 impact factor of 1.23), which is published jointly with the Association of Polish Neuropathologists. The scope of the journal covers basic, experimental and clinical neuroscience.