Assistant (f/m/x) in the Department of Neurogenetics and Functional Genomics

Assistant (f/m/x)
in the Department of Neurogenetics and Functional Genomics

City: Warsaw
Position: Assistant (f/m/x)                                                                             
Scientific discipline: medical sciences
Announcement date: April 27th, 2026
Application deadline: May 12th, 2026
Expected date of competition results announcement: the second half of May 2026
Date of taking the position: May/June 2026

Link to page: Department of Neurogenetics and Functional Genomics

The current research program of the Department of Neurogenetics and Functional Genomics:

  • functional studies of the underlying mechanisms of familial Alzheimer’s disease, with a particular focus on synaptic dysfunction, using a model based on reprogrammed human neurons and brain organoids
  • identification and comprehensive characterization (including bioinformatics) of mutations and genomic variants associated with the clinical phenotype of CUN neurodegenerative diseases, muscular, neurodevelopmental, neuropsychiatric, and related disorders
  • analysis of cellular and molecular processes (including mitochondrial function and mitophagy) underlying frontotemporal dementia (FTD) spectrum disorders caused by mutations in the PGRN, MAPT, and C9orf72 genes
  • development of new cellular models using iPSC lines derived from patients with frontotemporal dementia (FTD) caused by progranulin (PGRN) deficiency and new mutations detected by whole-genome sequencing
  • identification and comprehensive characterization of nuclear and mitochondrial genome variants relevant to achieving outstanding athletic performance

The area of the research in which the candidate would participate:

  • in vitro functional studies of synaptic dysfunction as an early sign of Alzheimer’s disease using an organoid model and reprogrammed neurons derived from patients with presenilin gene mutations
  • multiomic studies of the early stages of Alzheimer's disease
  • participation in the development of a platform providing access to brain organoid models from patients with neurodegenerative diseases, for the purpose of testing research hypotheses with translational potential

Description of job position activities:

  • conducting cell culture experiments (human neurons, 2D) and organoid culture experiments (brain organoids, 3D)
  • conducting functional studies of synaptic and epigenetic markers in vitro models
  • assisting with electrophysiological recordings (patch-clamp in whole-cell configuration) and analysis using microelectrode array (MEA) technology, as well as calcium response recordings (GCAMP8, Fura2-AM)
  • active participation in the scientific and organizational activities of the Department and the Institute
  • initiative and commitment to solving experimental tasks, analyzing, interpreting, and discussing results
  • preparing publications based on the obtained results
  • representing the Department and the Institute at scientific conferences

Requirements:

  • a master’s degree (or equivalent) in biological or medical sciences
  • proficiency in cell biology techniques (cell and tissue culture), molecular biology, and confocal microscopy
  • good knowledge of bioinformatics methods and statistical data analysis
  • independence and good work organization
  • creativity, ability to work in a team
  • preference for MMRI PAS as the primary place of employment
  • good or very good command of English

Additional requirements (desirable):

  • experience with organoid culture methods
  • knowledge of electrophysiological measurement methods
  • authoring or co-authoring of scientific publications

We offer:

  • employment at one of the leading scientific institutions in Poland
  • employment contract (full-time position)
  • opportunity for scientific development and independence in project management for which funding was obtained independently by the candidate
  • participation in the implementation of other projects
  • opportunity to attend conferences and to participate in internships abroad
  • additional support from the social fund (i.e. support in difficult life situations, childcare subsidies and low interest loans)
  • possibility to join Employee Capital Plans (PPK)
  • additional benefits such as opportunity to join a group life insurance program, medical service package, and a Multisport card on preferential terms
  • work in a good team, in a nice atmosphere
  • friendly work environment

Required documents:

  • cover letter with information about scientific interests
  • curriculum vitae containing information on education, scientific achievements, and previous jobs
  • list of publications
  • a copy of the diploma confirming the possession of the required professional title or academic degree
  • documents confirming the fulfillment of other requirements specified in the announcement of the competition

 

How to apply:
The application should be addressed to the Director of Mossakowski Medical Research Institute, Polish Academy of Sciences. The required documents in electronic form (pdf format only) should be sent to the following e-mail address: This email address is being protected from spambots. You need JavaScript enabled to view it. and must be received by the Institute by May 12th, 2026.

Please include the following job offer identification number in your application:  SDI.111.9.2026.
The date of receipt of documents by IMDiK PAN is decisive - the applications received after the deadline will not be considered.
Anticipated result announcement date: the second half of May 2026
Envisaged job starting date: May/June 2026

The competition is carried out following Employment Rules and Regulations for the position of the Researcher in MMRI PAS.

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