Electron Microscopy Research Unit

Head
Małgorzata Frontczak-Baniewicz, Assoc. Prof., Ph.D., phone: +48 22 60 86 585, This email address is being protected from spambots. You need JavaScript enabled to view it.

Research staff
Magdalena Gewartowska, Ph.D., phone: +48 22 60 86 412 , This email address is being protected from spambots. You need JavaScript enabled to view it.
Karolina Zajdel, Ph.D, phone: +48 22 60 86 412, This email address is being protected from spambots. You need JavaScript enabled to view it.

Technical staff
Joanna Kruss, M.Sc., phone: +48 22 60 86 412, This email address is being protected from spambots. You need JavaScript enabled to view it.
Grażyna Madejska, Eng., phone: +48 22 60 86 584,
Ryszard Strzałkowski, phone: +48 22 60 86 583, This email address is being protected from spambots. You need JavaScript enabled to view it.

 

Graduate students

Research profile
• Evaluation of ultrastructural changes in the myocardium in patients with cardiomyopathy
• Examination of the ultrastructure of tissues and organs (on clinical and experimental material)

Grants

Collaboration
domestic
foreign

Research equipment
• Transmission electron microscope model JEM 1011 (JEOL) equipped with a model EDS INCA (Oxford) analyzer
• Scanning electron microscope model JSM-6390LV (JEOL)

Research methods
• Morphological analysis in transmission microscope
• Morphological analysis in scanning microscope
• Immunocytochemical studies using colloidal gold and quantum dots
• In situ hybridization
• Negative staining

Selected publications

  • Pawlak A, Niedźwiedzka A, Gewartowska M, Przybylski M, Szułdrzyński K. SARS-CoV-2 and Cytomegalovirus Coinfection in a Patient With Myocarditis and Severe COVID-19 Infection. Can J Cardiol. 2023;39(7):988-989. doi:10.1016/j.cjca.2023.03.022

  • Zajdel K, Bartczak D, Frontczak-Baniewicz M, et al. Nano-bio interactions of upconversion nanoparticles at subcellular level: biodistribution and cytotoxicity. Nanomedicine (Lond). 2023;18(3):233-258. doi:10.2217/nnm-2022-0320

  • Gąssowska-Dobrowolska M, Czapski GA, Cieślik M, et al. Microtubule Cytoskeletal Network Alterations in a Transgenic Model of Tuberous Sclerosis Complex: Relevance to Autism Spectrum Disorders. Int J Mol Sci. 2023;24(8):7303. doi:10.3390/ijms24087303

  • Zajdel K, Janowska J, Frontczak-Baniewicz M, Sypecka J, Sikora B. Upconverting Nanoparticles as a New Bio-Imaging Strategy-Investigating Intracellular Trafficking of Endogenous Processes in Neural Tissue. Int J Mol Sci. 2023;24(2):1122. doi:10.3390/ijms24021122

  • Kawalec M, Wojtyniak P, Bielska E, et al. Mitochondrial dynamics, elimination and biogenesis during post-ischemic recovery in ischemia-resistant and ischemia-vulnerable gerbil hippocampal regions. Biochim Biophys Acta Mol Basis Dis. 2023;1869(3):166633. doi:10.1016/j.bbadis.2022.166633

  • Dąbrowska-Bouta B, Sulkowski G, Gewartowska M, Strużyńska L. Endoplasmic Reticulum Stress Underlies Nanosilver-Induced Neurotoxicity in Immature Rat Brain. Int J Mol Sci. 2022;23(21):13013. doi:10.3390/ijms232113013

  • Pawlak A, Gewartowska M, Przybylski M, et al. Ultrastructural Changes in Mitochondria in Patients with Dilated Cardiomyopathy and Parvovirus B19 Detected in Heart Tissue without Myocarditis. J Pers Med. 2022;12(2):177. 28. doi:10.3390/jpm12020177

  • Trochimczuk M, Gewartowska M, Stańczyk M. Endovascular treatment of a giant splenic artery aneurysm. Pol Arch Intern Med. 2022;132(3):16180. doi:10.20452/pamw.16180

  • Stanaszek L, Majchrzak M, Drela K, et al. Myelin-Independent Therapeutic Potential of Canine Glial-Restricted Progenitors Transplanted in Mouse Model of Dysmyelinating Disease. Cells. 2021;10(11):2968.

  • Domaszewska-Szostek A, Gewartowska M, Stanczyk M, Narowska B, Moscicka-Wesołowska M, Olszewski WL. An Anhydrous Sodium Chloride Skin Preservation Model for Studies on Keratinocytes Grafting into the Wounds. Pharmaceutics. 2021;13(12):2078. doi:10.3390/pharmaceutics13122078

  • Czapski GA, Babiec L, Jęśko H, et al. Synaptic Alterations in a Transgenic Model of Tuberous Sclerosis Complex: Relevance to Autism Spectrum Disorders. Int J Mol Sci. 2021;22(18):10058. doi:10.3390/ijms221810058

  • Skalska J, Dąbrowska-Bouta B, Frontczak-Baniewicz M, Sulkowski G, Strużyńska L. A low dose of nanoparticulate silver induces mitochondrial dysfunction and autophagy in adult rat brain. Neurotox Res. 2020;38(3):650-664. DOI:10.1007/s12640-020-00239-4. 
  • Kamińska I, Jankowski D, Sikora B, Kowalik P, Minikayev R, Wojciechowski T, Chojnacki M, Sobczak K, Rybusiński J, Szczytko J, Zajdel K, Suchocki A, Paszkowicz W, Frontczak-Baniewicz M, Fronc K. Structural, optical and magnetic properties of Y3-0.02-xEr0.02Yb x Al5O12 (0 < x < 0.20) nanocrystals: effect of Yb content. Nanotechnology. 2020;31(22):225711. DOI:10.1088/1361-6528/ab73b9. 
  • Cieślik M, Gąssowska-Dobrowolska M, Jęśko H, Czapski GA, Wilkaniec A, Zawadzka A, Dominiak A, Polowy R, Filipkowski RK, Boguszewski PM, Gewartowska M, Frontczak-Baniewicz M, Sun GY, Beversdorf DQ, Adamczyk A. Maternal immune activation induces neuroinflammation and cortical synaptic deficits in the adolescent rat offspring. Int J Mol Sci. 2020;21(11):4097. DOI:10.3390/ijms21114097. 
  • Gąssowska-Dobrowolska M, Cieślik M, Czapski GA, Jęśko H, Frontczak-Baniewicz M, Gewartowska M, Dominiak A, Polowy R, Filipkowski RK, Babiec L, Adamczyk A. Prenatal exposure to valproic acid affects microglia and synaptic ultrastructure in a brain-region-specific manner in young-adult ale rats: relevance to autism spectrum disorders. Int J Mol Sci. 2020;21(10):3576. DOI:10.3390/ijms21103576. 
  • Dabrowska S, Del Fattore A, Karnas E, Frontczak-Baniewicz M, Kozlowska H, Muraca M, Janowski M, Lukomska B. Imaging of extracellular vesicles derived from human bone marrow mesenchymal stem cells using fluorescent and magnetic labels. Int J Nanomedicine. 2018;13:1653-1664. DOI:10.2147/IJN.S159404. eCollection 2018. 
  • Pawlak A, Wiligorska N, Wiligorska D, Frontczak-Baniewicz M, Przybylski M, Krzyzewski R, Ziemba A, Gil RJ. Viral heart disease and acute coronary syndromes - often or rare coexistence? Curr Pharm Des. 2018;24(4):532-540. DOI:10.2174/1381612824666171227220253. 
  • Dąbrowska-Bouta B, Sulkowski G, Frontczak-Baniewicz M, Skalska J, Sałek M, Orzelska-Górka J, Strużyńska L. Ultrastructural and biochemical features of cerebral microvessels of adult rat subjected to a low dose of silver nanoparticles. Toxicology. 2018;408:31-38. DOI:10.1016/j.tox.2018.06.009. 
  • Kamińska I, Elbaum D, Sikora B, Kowalik P, Mikulski J, Felcyn Z, Samol P, Wojciechowski T, Minikayev R, Paszkowicz W, Zaleszczyk W, Szewczyk M, Konopka A, Gruzeł G, Pawlyta M, Donten M, Ciszak K, Zajdel K, Frontczak-Baniewicz M, Stępień P, Łapiński M, Wilczyński G, Fronc K. Single-step synthesis of Er3+ and Yb3+ ions doped molybdate/Gd2O3 core-shell nanoparticles for biomedical imaging. Nanotechnology. 2018;29(2):025702. DOI:10.1088/1361-6528/aa9974. 
  • Ziemka-Nalecz M, Janowska J, Strojek L, Jaworska J, Zalewska T, Frontczak-Baniewicz M, Sypecka J. Impact of neonatal hypoxia-ischaemia on oligodendrocyte survival, maturation and myelinating potential. J Cell Mol Med. 2018;22(1):207-222. DOI:10.1111/jcmm.13309. 
  • Popek M, Bobula B, Sowa J, Hess G, Polowy R, Filipkowski RK, Frontczak-Baniewicz M, Zabłocka B, Albrecht J, Zielińska M. Cortical synaptic transmission and plasticity in acute liver failure are decreased by presynaptic events. Mol Neurobiol. 2018;55(2):1244-1258. DOI:10.1007/s12035-016-0367-4.

Patents
• P.404667 (12.12.2016).
The application of polymer nanofibers insulating mesh manufactured with the use of electrospinning technology for the production of neuroprotective dressings for prevention of post-traumatic brain lesions.