World Rare Disease Day 2025
"Rare diseases in a multidimensional perspective" Conference
For eight years now, as part of the celebration of World Rare Disease Day (rarediseaseday.org),
we have been co-organizing a unique event that brings together experts, researchers, patients and their families.
This year, we invite you to the Conference entitled "Rare diseases in a multidimensional perspective", which will take place on February 28, 2025 from 9:30 a.m. to 3:30 p.m. Participation in the event is free of charge, registration is required. The conference will be accompanied by workshops of the School of Molecular Genetics of the IMiD Foundation (registration), which will take place on February 27, 2025 at the IMiD.
The co-organizers of this important event are, in addition to our Institute, the Institute of Biochemistry and Biophysics of the Polish Academy of Sciences, the Institute of Mother and Child, the EB Polska Foundation, the Polish Biochemical Society and the Polish Alzheimer's Society.
This year's conference highlights the complexity of the issue of rare diseases, which require a coordinated approach - from diagnostics through therapy to comprehensive social support. These diseases are not only a medical challenge, but also a scientific, social and therapeutic one. During the conference, we will focus on the issues of access to therapy for Polish patients with rare diseases, the role of basic science and modern technologies, including artificial intelligence, in diagnostics and the creation of targeted drugs, as well as the importance of international cooperation, including the activities of the European Alliance for Rare Disease Research (EJPRD).
Although rare diseases affect a relatively small number of people, their impact on the lives of patients and their families is enormous.
By participating in this Conference, you will be able to learn about the latest achievements in research and therapy of rare diseases and gain insight into the problems of access to treatment and care in Poland. We also hope that participating in the Conference will become an inspiration to build a network of cooperation between scientists, clinicians and patient organizations.
This event is not only a space for exchanging knowledge and experiences, but also an opportunity to strengthen actions to improve the quality of life of patients with rare diseases.
Conference website: O konferencji - Choroby Rzadkie 2025
Cancer Fight Research Club-new season
The project is financed from the state budget, allocated by the Minister of Science and Higher Education under the Science for the Society II Programme
Prof. Mikołaj Słabicki-lecture invitation
On behalf of our Department of Immunology we cordially invite to the lecture of
prof. Mikołaj Słabicki
"Novel Mechanisms of Small Molecule-Induced Protein Degradation"
which will take place on December 9, 2024 at 15.00 via the Microsoft Teams platform (link below).
Mikołaj Słabicki is a professor at Harvard Medical School and head of a research group at the Mass General Cancer Center.
Prof. Słabicki's team is engaged in discovering new mechanisms of degradation of pathogenic proteins, potentially susceptible to pharmacological modulation. This research focuses on the mechanisms of removal of unnecessary or damaged proteins, with particular emphasis on E3 ligases responsible for marking proteins for degradation. Using methods of functional genomics, cell biology, bioinformatics, molecular biology, and chemical and biochemical tools, scientists from Prof. Słabicki's group reprogram the ubiquitin-proteasome system to identify and characterize new therapeutic possibilities. Their research not only expands basic biological knowledge but also contributes to the creation of new therapies for diseases that currently have no available treatment options.
Use the link below to join the meeting:
https://teams.microsoft.com/l/meetup-join/19%3ameeting_N2E0MzhjNWQtNzE5OC00MDZkLWI3ODUtZmJkNGYwOGRiM2Nm%40thread.v2/0?context=%7b%22Tid%22%3a%226d67227e-b5e2-454a-9abd-356edc31e10c%22%2c%22Oid%22%3a%22cb5131e9-cad1-41bb-9177-91ffcd721a49%22%7d
Congratulations to NCN Grant Laureates!
MMRI PAS researchers awarded in the OPUS 27 and PRELUDIUM 23 National Science Centre competitions!
OPUS 27
Prof. Agnieszka Piwkowska
Head of Laboratory of Molecular and Cellular Nephrology
Małgorzata Firczuk, PhD
Immunology Department
In the consortium with Medical University of Lodz – the project leader
Principal Investigator: Agata Pastorczak MD, PhD from Department of Pediatrics, Oncology, Hematology and Diabetology Medical University of Lodz
PRELUDIUM 23
Kamil Adamiak, MSc
Laboratory of Pathological Neurochemistry
Congratulations!
Polish Academy of Sciences Scientific Award
The team of the Molecular and Cellular Nephrology Laboratory from Gdańsk, headed by prof. Agnieszka Piwkowska, consisting of:
dr hab. Irena Audzeyenka
dr hab. Dorota Rogacka, prof. IMDiK
and dr Patrycja Rachubik
was honored with the Scientific Award of the Division V of Medical Sciences of the Polish Academy of Sciences for a series of publications entitled
"The role of insulin in the regulation of the metabolic function of podocyte cells in physiological conditions and hyperglycemia."
Diabetic nephropathy is one of the most common and most serious complications of diabetes, leading to chronic renal failure in about 30-40% of patients. Since 2005, when the elements of the classic signaling pathway for insulin in podocytes were first identified, numerous studies have been conducted that have shown the influence of this hormone not only on the activation of extracellular glucose uptake, but also on a number of other processes that are key to the biology and physiology of podocytes. This scientific achievement is closely related to understanding the mechanisms responsible for regulating the function and metabolism of podocyte cells, with particular emphasis on understanding the signaling pathways whose disorders in hyperglycemia or hyperinsulinemia lead to damage to these cells and, consequently, to damage to the glomerular filtration barrier.”
We sincerely congratulate the entire Team and wish them further success!
