Projects implemented at MMRI PAS funded by the Polish National Agency for Academic Exchange (Polish NAWA)
The assessment of neuroprotective and immunomodulating properties of exosomes derived from adipose-derived mesenchymal stem cells in amyotrophic lateral sclerosis models.
Project manager: Sylwia Dąbrowska MD PhD
Project implemented as scholarship at the University of Verona
International collaboration: Italy
Mieczysław Bekker Programme 2019, implementation period: 2020 – 2022, project funding: PLN 223 000
Comprehensive characteristics of genomic variants associated with Tourette's syndrome.
Project manager: Jakub Fichna MD PhD
Project implemented as scholarship at Purdue University
International collaboration: USA
Mieczyslaw Bekker Programme 2020, implementation period: 2021 – 2022, project funding: PLN 156 000
Exosome-mediated enhancement of immunotherapy against glioblastoma – the role of non-coding RNA.
Project manager: Jakub Godlewski MD PhD
Polskie Powroty 2019 call, implementation period: 2020 – 2024, project funding: PLN 2 270 000
The objective of the project is to develop and validate an innovative therapeutic approach using extracellular vesicles (EVs) as carriers for therapeutic microRNAs in the treatment of brain tumors. The project aims to establish standardized protocols for EV isolation and analysis, build a biobank of human cell lines, optimize microRNA loading methods, and identify EV sources with regenerative and immunomodulatory properties. Further goals include investigating EV–immune system interactions and developing preclinical models to assess therapeutic safety and efficacy. The project is designed to lay the groundwork for future clinical applications of EV-based therapies in brain tumors and other degenerative diseases.
Exploring pro-inflammatory interleukins as major players in the link carotid body-metabolic deregulation in obesity and obstructive sleep apnea
Project manager: Kryspin Andrzejewski
Project implemented in partnership with Universidade Nova de Lisboa
International collaboration: Portugal
The NAWA Joint Research projects call between the Republic of Poland and the Republic of Portugal, implementation period: 2022 – 2024, project funding: PLN 24 800